Combinatorial Chemoenzymatic Synthesis and High-Throughput Screening of Sialosides
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چکیده
منابع مشابه
Combinatorial chemoenzymatic synthesis and high-throughput screening of sialosides.
Although the vital roles of structures containing sialic acid in biomolecular recognition are well documented, limited information is available on how sialic acid structural modifications, sialyl linkages, and the underlying glycan structures affect the binding or the activity of sialic acid-recognizing proteins and related downstream biological processes. A novel combinatorial chemoenzymatic m...
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ژورنال
عنوان ژورنال: ACS Chemical Biology
سال: 2008
ISSN: 1554-8929,1554-8937
DOI: 10.1021/cb800127n